CURING THE DRUG RESISTANCE PLASMID IN E. COLI O157:H7

Plasmid interference for curing antibiotic resistance plasmids in vivo

Antibiotic resistance increases the likelihood of death from infection by common pathogens such as Escherichia coli and Klebsiella pneumoniae in developed and developing countries alike. Most important modern antibiotic resistance genes spread between such species on self-transmissible (conjugative) plasmids. These plasmids are traditionally grouped on the basis of replicon incompatibility (Inc...

Plasmid curing in bacteria pdf

Plasmids are extrachromosomal pieces of double-stranded circular DNA which have the capability to replicate independently of the.Growth dynamics of multiple component communities of bacteria. Thus curing by acridines normally involves loss of the whole plasmid.Plasmids are extrachromasomally replicating molecules of DNA present in bacteria.Plasmid curing is a process of completely removing plas...

Comparison of two methods for detection of E. coli O157H7 in unpasteurized milk

BACKGROUND AND OBJECTIVES The most common serotype of enterohaemorrhagic Esherichia coli group or Shiga-toxin-producing E. coli is O157:H7. Domestic and wild ruminants are regarded as the main natural reservoirs. O157:H7 serotype is the major cause of gastrointestinal infections in developed countries. In this study was conducted to survey on the toxigenic E. coli O157: H7 strains in milk of in...

Biocide Resistance in E. coli

More than 40,000 cases of food-borne infection by the bacteria Campylobacter, Staphylococcus, Salmonella, and E. coli, resulting in about 500 deaths, occur every year in the United States (Cohen & Tauxe, 1986). These infections result from contact with contaminated beef products, poultry, eggs, or water. In response to consumer concern about unsafe foods and other sources of infection, manufact...

Mecillinam Resistance in E. coli